How is Serostim® injected?

Serostim® (somatropin) for injection is a medicine that is self-injected, which means you can inject it in the convenience of your home.

Serostim® is injected under the skin, subcutaneously, through a short and thin needle. Serostim® can be self-administered every day or every other day, usually at bedtime, as prescribed by your healthcare provider. Training is offered to help you learn how to give yourself injections. Injection training can be scheduled at your home, your healthcare provider’s office, or another location, such as your pharmacy or local service organization.

Serostim® offers in-home or in-office injection training provided through a national network of product administration trainers. Patient support is available 24/7 to assist patients with treatment education and support.

Here’s what you’ll need for a Serostim® injection:

Please read all instructions FIRST before taking Serostim®.

  • The Serostim® vial containing the medication in a freeze-dried powder
  • A vial containing diluent (a liquid that you will mix with the Serostim® powder)
  • A syringe used to mix the diluent with the Serostim® powder
  • Two needles:
    • A longer, 20-gauge needle to add the diluent to the Serostim® vial and withdraw the solution before the injection
    • A shorter, 30-gauge needle to administer the injection
  • Alcohol swabs to clean the skin before the injection and to wipe the vial tops
  • A bandage or gauze pad to cover the injection site
  • Sharps container to dispose of needles and syringes
  • Disposable gloves if someone else is giving the injection
  • Medication, needles and syringes are supplied by the pharmacy

Note: Make sure all injection items are unopened before use. If you find an open needle or syringe packet, do not use it. Dispose of it in your sharps container. Needles and syringes should never be shared or reused.


As of April 1st, 2017, the® 2 is no longer available to new patients given a Serostim prescription.

For those patients currently administering Serostim with the® 2, EMD Serono will continue to provide patient support services, including injection training.

At this time, we expect to be able to provide device replacement and ancillary supplies through March 2018. If you’re a patient using® 2, please contact the AXIS Center for more information at 1-877-714-AXIS (2947).

Please read all instructions FIRST before taking Serostim®.

Here’s what you’ll need for a® 2 injection:

  •® 2 device ordered by your healthcare provider
  • Serostim® vial
  • A vial containing diluent (a liquid that you will mix with Serostim® powder)
  • Nozzle and piston set
  • Alcohol swabs
  • Sterile gauze pad or cotton ball
  • Reconstitution kit


  • Physician or nurse training should be provided to you before you use® 2
  •® 2 must be used only with Serostim® and not with any other brand of human growth hormone or medication
  • As with any injection device, improper use of® 2 may result in injury, including the transmission of blood-borne diseases. Adhere to strict safety and antiseptic precautions at all times

Important Information for® 2

  • In order to use® 2 properly, you must first understand and follow steps described on the video on this page. It is important to use® 2 only as indicated and replace disposable parts as recommended
  • Patients who use® 2 must be able to see the numbers on the dose display clearly, turn the rear housing unit easily, and press the release button
  •® 2 should not be used in patients who have low platelet counts, bruise or bleed easily, are taking anticoagulants (blood thinners), or are taking other medication/ therapy that may contribute to excess bleeding or bruising. Hemophiliacs should not use this device
  •® 2 is not recommended for patients who do not have adequate subcutaneous tissue or normal hematopoietic function
  • If after trying a variety of delivery sites you are still unable to use® 2 comfortably, contact your doctor or nurse
  •® 2 is available by prescription only

The AXIS Center is a support program offered by EMD Serono, the maker of Serostim®. It offers in-home or in-office injection training. Support is available 24/7 to help answer your Serostim® questions at 1-877-714-AXIS (2947).

Important information: